Breast Carcinoma: From Initial Tumor Cell Detachment to Settlement at Secondary Sites
نویسندگان
چکیده
منابع مشابه
Breast Carcinoma: From Initial Tumor Cell Detachment to Settlement at Secondary Sites
Metastasis represents a multistep cascade of cancer cell alterations accompanied by structural and functional changes within the tumor microenvironment which may involve the induction of a retrodifferentiation program. Major steps in metastatic developments include (A) cell detachment from the primary tumor site involving epithelial-mesenchymal transition (EMT), (B) migration and invasion into ...
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ژورنال
عنوان ژورنال: BioMed Research International
سال: 2017
ISSN: 2314-6133,2314-6141
DOI: 10.1155/2017/8534371